Stephen L Hoffman Selected Research

Malaria Vaccines

1/2022	Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa.
2/2021	Nanotechnological immunoassay for rapid label-free analysis of candidate malaria vaccines.
1/2021	Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2.
11/2020	Providing Ancillary Care in Clinical Research: A Case of Diffuse Large B-Cell Lymphoma during a Malaria Vaccine Trial in Equatorial Guinea.
1/2020	Effect of immune regulatory pathways after immunization with GMZ2 malaria vaccine candidate in healthy lifelong malaria-exposed adults.
1/2020	The Equatoguinean Malaria Vaccine Initiative: From the Launching of a Clinical Research Platform to Malaria Elimination Planning in Central West Africa.
1/2019	Controlled Human Malaria Infection of Healthy Adults With Lifelong Malaria Exposure to Assess Safety, Immunogenicity, and Efficacy of the Asexual Blood Stage Malaria Vaccine Candidate GMZ2.
1/2019	Malaria vaccine trials in pregnant women: An imperative without precedent.
12/2017	Protection against Plasmodium falciparum malaria by PfSPZ Vaccine.
1/2017	Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice.

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Stephen L Hoffman Research Topics

Disease

137	Malaria 10/2022 - 01/2002
84	Infections 10/2022 - 03/2003
18	Bites and Stings (Sting) 01/2020 - 01/2010
16	Parasitemia 02/2022 - 03/2002
11	Falciparum Malaria (Plasmodium falciparum Malaria) 04/2019 - 03/2002
6	Vivax Malaria 01/2019 - 10/2002
4	Parasitic Diseases (Parasitic Disease) 01/2017 - 11/2015
3	Communicable Diseases (Infectious Diseases) 01/2021 - 07/2013
3	Anemia 10/2002 - 03/2002
2	Typhoid Fever (Typhoid) 01/2017 - 01/2017
2	Hepatocellular Carcinoma (Hepatoma) 12/2010 - 07/2003
2	Human Influenza (Influenza) 04/2010 - 10/2006
1	Inflammation (Inflammations) 07/2021
1	Coinfection 01/2021
1	Virus Diseases (Viral Diseases) 01/2021
1	Viremia 01/2021
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 11/2020
1	Lymphadenopathy 11/2020
1	Sickle Cell Trait 01/2018
1	Inhalation anthrax 01/2017
1	Anthrax 01/2017
1	Bacillary Dysentery (Shigellosis) 01/2017
1	Fatigue 01/2017
1	Fever (Fevers) 01/2017
1	Headache (Headaches) 01/2017
1	Myalgia 01/2017
1	Infertility (Sterility) 04/2015
1	Chest Pain (Chest Pains) 01/2014
1	Myocarditis (Carditis) 01/2014

Drug/Important Bio-Agent (IBA)

84	VaccinesIBA 10/2022 - 03/2002
51	1- acetyl- 1,2,3,3a,8,8a- hexahydro- 8a- hydroxy- 5- methoxypyrrolo(2,3- b)indole (CHMI)IBA 06/2022 - 01/2013
24	Malaria VaccinesIBA 01/2022 - 09/2003
16	AntigensIBA 06/2022 - 06/2009
15	AntibodiesIBA 02/2022 - 07/2003
14	Proteins (Proteins, Gene)FDA Link 05/2022 - 02/2002
14	Pharmaceutical PreparationsIBA 01/2019 - 03/2002
11	Chloroquine (Aralen)FDA LinkGeneric 01/2021 - 06/2002
9	Antimalarials (Antimalarial Agents)IBA 01/2021 - 10/2002
7	DNA (Deoxyribonucleic Acid)IBA 07/2013 - 03/2002
6	Immunoglobulin G (IgG)IBA 09/2021 - 01/2017
6	DNA VaccinesIBA 11/2012 - 03/2002
5	Primaquine FDA Link 01/2019 - 06/2002
4	Recombinant ProteinsIBA 01/2021 - 06/2002
4	Surface Antigens (Surface Antigen)IBA 01/2019 - 07/2013
4	Monoclonal AntibodiesIBA 01/2019 - 01/2017
4	proguanil drug combination atovaquone (malarone)FDA Link 01/2017 - 10/2002
3	Merozoite Surface Protein 1 (MSA1)IBA 06/2022 - 02/2004
3	CytokinesIBA 01/2021 - 08/2002
3	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2021
3	18S Ribosomal RNAIBA 08/2020 - 07/2018
3	Biomarkers (Surrogate Marker)IBA 08/2020 - 07/2018
3	Nucleic AcidsIBA 01/2020 - 01/2015
3	Hemoglobins (Hemoglobin)IBA 01/2018 - 03/2002
3	Complement System Proteins (Complement)IBA 01/2018 - 02/2013
2	Ribosomal DNA (rDNA)IBA 03/2022 - 07/2018
2	InterferonsIBA 07/2021 - 01/2021
2	Indicators and Reagents (Reagents)IBA 01/2021 - 01/2020
2	Aluminum Hydroxide (Algeldrate)FDA Link 01/2021 - 01/2019
2	ChemokinesIBA 01/2021 - 07/2010
2	N-acetyltalosaminuronic acid (NAT)IBA 01/2019 - 01/2015
2	Immunoglobulin M (IgM)IBA 01/2018 - 01/2018
2	Mefloquine (Lariam)FDA LinkGeneric 01/2017 - 02/2007
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 11/2012 - 07/2002
2	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 12/2003 - 03/2003
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 10/2022
1	Immunoglobulin A (IgA)IBA 09/2021
1	Pyrimethamine (Daraprim)FDA Link 01/2021
1	Rabies Vaccines (Rabies Vaccine)FDA Link 01/2021
1	5' Untranslated Regions (5' UTR)IBA 01/2021
1	Interleukin-17 (Interleukin 17)IBA 01/2021
1	Polysaccharides (Glycans)IBA 01/2021
1	Interleukin-2 (IL2)IBA 01/2021
1	Saline SolutionIBA 01/2020
1	ProteomeIBA 01/2020
1	Recombinases (Recombinase)IBA 01/2020
1	Histidine (L-Histidine)FDA Link 11/2019
1	Biological ProductsIBA 10/2019
1	Endothelial Protein C ReceptorIBA 01/2019
1	artemisinin (artemisinine)IBA 12/2018
1	ArtesunateIBA 12/2018
1	cyclopropapyrroloindoleIBA 01/2018
1	indoleIBA 01/2018
1	ImmunosorbentsIBA 01/2017
1	EnzymesIBA 01/2017
1	DSM265IBA 01/2017
1	GlycolipidsIBA 09/2015
1	Histocompatibility Antigens Class IIIBA 09/2015
1	Immune Sera (Antisera)IBA 04/2015
1	EndotoxinsIBA 04/2015
1	Fatty Acids (Saturated Fatty Acids)IBA 05/2014
1	B-Cell Activation Factor ReceptorIBA 04/2014
1	Sialic AcidsIBA 04/2011

Therapy/Procedure

8	Therapeutics 12/2018 - 06/2002
7	Chemoprevention 01/2021 - 03/2003
3	Injections 01/2021 - 12/2015
3	Intradermal Injections 05/2015 - 01/2013
2	Intravenous Injections 01/2017 - 01/2016
2	Mass Drug Administration 01/2017 - 12/2015
1	Intramuscular Injections 01/2014
1	Jet Injections 11/2012